Pyramis Studios, formed in 1999, combines acclaimed visualization, design, and communication skills with training in the biomedical sciences to create high-impact media for clients with exacting standards for scientific accuracy.
Scientific training
Research and teaching experience
Visualization and design expertise
Computer science training and experience

Our cross-disciplinary expertise enables the most efficient and effective translation of your scientific message into the end product.
The biomedical media that we create is genuinely informed by the science.
Many biomedical illustrators, animators and web developers possess artistic and/or computer training but lack expertise in the scientific disciplines that they are charged to represent. At Pyramis Studios, our training and academic experience provides us with the ability to understand the complex concepts and vocabulary at the core of the biotechnology and healthcare industries. Understanding the language of biology and medicine allows us to most efficiently and effectively translate your scientific message into the end product.
Many biomedical illustrators, animators and web developers possess artistic and/or computer training but lack expertise in the scientific disciplines that they are charged to represent. At Pyramis Studios, our training and academic experience provides us with the ability to understand the complex concepts and vocabulary at the core of the biotechnology and healthcare industries. Understanding the language of biology and medicine allows us to most efficiently and effectively translate your scientific message into the end product.
S. Mark Williams
Creative Director/President
Creative Director/President
Williams is the lead illustrator, animator, and graphic designer at Pyramis.
A.B., Davidson College
M.Phil, Yale University
Ph.D., Yale University
M.Phil, Yale University
Ph.D., Yale University
Williams is a graduate of Davidson College where he studied pre-medicine and psychology. He earned an M.Phil and Ph.D. in neurobiology from Yale University. Working with Patricia Goldman-Rakic at Yale, Williams examined the anatomy of the cortical dopamine system in primates in the context of schizophrenia and Parkinson's Disease. Following a year of teaching at Davidson College, Williams moved to Duke University Medical Center as a postdoctoral fellow in the laboratory of Dale Purves in the Department of Neurobiology. In addition to conducting research on the visual system, Williams began work on a series of unique interactive software applications used to facilitate the understanding of the complex anatomy of the human central nervous system. These efforts culminated in the publication of series of CD-ROM brain atlases, including Sylvius: Fundamentals of Human Neural Structure and SylviusPRO. Williams also began merging his artistic skills with his scientific training by illustrating biomedical textbooks and founded Pyramis Studios, Inc. in 1999 to further develop this hybrid of science and media development.
Williams remains an adjunct member of the faculty at Duke University Medical Center where he is a Senior Research Scientist in the Department of Neurobiology. Since 2001, he has been co-director of the medical neurobiology course for first year medical students. He also teaches a course in clinical neuroanatomy to undergraduate pre-medical and psychology students at Duke. Williams has published numerous neuroanatomical research papers and is an editor of the successful introductory text, Neuroscience, published by Sinauer Associates.
Williams remains an adjunct member of the faculty at Duke University Medical Center where he is a Senior Research Scientist in the Department of Neurobiology. Since 2001, he has been co-director of the medical neurobiology course for first year medical students. He also teaches a course in clinical neuroanatomy to undergraduate pre-medical and psychology students at Duke. Williams has published numerous neuroanatomical research papers and is an editor of the successful introductory text, Neuroscience, published by Sinauer Associates.
Mace is the technical architect of web and interactive projects at Pyramis.
A.B., Duke University
Mace is a graduate of Duke University where he studied biology and computer science. Interested in combining these disciplines and seeing a unique and compelling vision at Pyramis, he joined the team in 2001.
Prior to working at Pyramis, Mace developed high-profile regional and national web sites for Research Triangle Park firms including Synecor, LLC, and the North Carolina Technological Development Authority, Inc. At Pyramis, Mace is the technical architect of web and interactive projects. He is fluent in Perl, C, HTML, JavaScript, CSS, XML/XSL, ActionScript (Macromedia Flash), Internet protocols, and relevant standards and compliance.
Outside Pyramis, Mace is an accomplished acid jazz guitarist and performs regularly throughout North Carolina.
Prior to working at Pyramis, Mace developed high-profile regional and national web sites for Research Triangle Park firms including Synecor, LLC, and the North Carolina Technological Development Authority, Inc. At Pyramis, Mace is the technical architect of web and interactive projects. He is fluent in Perl, C, HTML, JavaScript, CSS, XML/XSL, ActionScript (Macromedia Flash), Internet protocols, and relevant standards and compliance.
Outside Pyramis, Mace is an accomplished acid jazz guitarist and performs regularly throughout North Carolina.
Nate O'Keefe
Project Management and Marketing Coordinator
Project Management and Marketing Coordinator
O'Keefe works with current and prospective clients to manage project details and deadlines.
B.A., University of North Carolina
O'Keefe holds a B.A. from the University of North Carolina at Chapel Hill in English and public policy analysis. At the Peabody School of Education at Vanderbilt University, he worked for several years with the team that developed the Institute for School Leaders web/computer-based training program.
Since returning to the Triangle to join Pyramis in 2002, O'Keefe has helmed the development teams for a variety of projects, including the Sylvius line of interactive neuroanatomical reference tools, the Interactive Brain Tumor Learning Center patient education web site, and a host of web development contracts. Additionally, O'Keefe provides audio/video recording and engineering services for web applications, and illustration and web programming support.
O'Keefe also operates a small independent recording studio for Pyramis soundtrack and voiceover projects, film scoring, and live and multi-track music recording.
Since returning to the Triangle to join Pyramis in 2002, O'Keefe has helmed the development teams for a variety of projects, including the Sylvius line of interactive neuroanatomical reference tools, the Interactive Brain Tumor Learning Center patient education web site, and a host of web development contracts. Additionally, O'Keefe provides audio/video recording and engineering services for web applications, and illustration and web programming support.
O'Keefe also operates a small independent recording studio for Pyramis soundtrack and voiceover projects, film scoring, and live and multi-track music recording.
Paige Harris
Illustrator
Illustrator
Harris provides 2D media creation support.
B.A., Savannah College of Art and Design
Harris is a graduate of the Savannah College of Art and Design where she received a B.A. in painting. She taught studio art and art history at Episcopal High School in Jacksonville, Florida, prior to serving as the Director of Communications at Episcopal. It was during this time that she began successfully blending her skills as a figurative painter with digital media techniques. She has since worked as a freelance designer and illustrator and continues to be an active painter.
At Pyramis, Harris has worked on numerous illustration projects including textbooks and web graphics. She is recognized for creating clean, informative and aesthetically pleasing illustrations and graphs.
At Pyramis, Harris has worked on numerous illustration projects including textbooks and web graphics. She is recognized for creating clean, informative and aesthetically pleasing illustrations and graphs.









